Ivermectin, ‘Wonder drug’ from Japan: the human use perspective
Streptomyces avermitilis is a species of bacteria in the genus Streptomyces. This bacterium was discovered by Satoshi Ōmura in Shizuoka Prefecture, Japan.
The first complete genome sequence of S. avermitilis was completed in 2003.[4] The genome consists of a single chromosome with a linear structure, unlike most bacterial genomes, which exist in the form of circular chromosomes.[5]
Avermectins are industrially derived from the fermentation products of S. avermitilis.[1][6] Avermectin itself was discovered by the Satoshi Ōmura group[6] and first disclosed in Burg et al. 1979.[1] One of the most widely employed drugs against nematode and arthropod infestations is the avermectin derivative ivermectin, as well as abamectin, a widely used insecticide and antihelmintic.
The following is a list of Streptomyces species, organized alphabetically by species name. Names that have not been validated according to the Bacteriological Code are enclosed in “quotes”.
As of June 2021, there are 679 valid species of Streptomyces and an additional 121 provisional species. New species continue to be discovered (e.g., S. gossypiisoli, described in 2021).Many species are named after their colorful hyphae and/or spores.